Buprenorphine, otherwise known as Probuphine and Subutex, is a medication which is used for the prevention
and treatment of opiate addiction, as well as pain relief.

Though this drug is typically used to prevent opiate addiction, it may also be prescribed for medical treatment of opioid induced constipation in cases where other medications have failed. Additionally, its antidepressant properties may be utilized to treat depression in severe cases when methadone has failed.

Buprenorphine is a partial opioid agonist, meaning that it binds to the same receptors as opioids and opiates, but with a limited effect. This allows for very effective treatment of pain, severe withdrawal symptoms and addiction disorders as it does not produce the intense high or euphoria that other opioids produce.

This drug is actually an extended release morphine formulation which comes in the form of a slow dissolving subdermal pellet injected into the area between the shoulder blades. The pellets are replaced every two or three months to maintain the drug’s effectiveness in preventing withdrawal, addiction and cravings after prolonged use.