Yes, you can take melatonin with Nyquil. However, before taking a medication that contains melatonin, it is essential that you check if it will react with any other medicines or supplements you might be taking. This article lists some of the more common interactions between these two medications and their potential side effects.

 

What is melatonin?

Melatonin is a hormone produced from the pineal gland that plays a key role in sleep patterns, mood, and the regulation of the immune system. According to the National Sleep Foundation, the production of this hormone is naturally regulated by light and darkness, with the highest levels being produced around bedtime.

Melatonin supplements are commonly used for sleep disorders such as insomnia, jet lag, shift work sleep disorder, and circadian rhythm disorders.

How does melatonin work?

Melatonin is an antioxidant that is involved in several of our body’s functions, including sleep patterns. It regulates your sleep–wake cycle by controlling the timing and duration of your sleep. Melatonin supplements are commonly used for sleep disorders such as insomnia, jet lag, shift work sleep disorder, and circadian rhythm disorders.

What are the side effects of taking Melatonin with Nyquil?

Melatonin supplements are generally considered to be safe. There are few interactions reported between melatonin and other medications, which is why it is often used as a sleeping aid. When taking melatonin with Nyquil, there is a risk of increased drowsiness, dizziness, and headaches due to the interaction of the two drugs. As melatonin is a hormone, there is a risk that it could negatively interact with other hormones in the body, including those in the reproductive system.

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Can you take Melatonin while breastfeeding?

Melatonin exhibits significant excretion in breast milk but, according to one study, only a small proportion of this amount enters the infant’s bloodstream. Other studies have found that melatonin levels in breastfed infants are as low as in non-breastfed infants, indicating that it does not affect a breastfeeding baby. Taking melatonin supplements while breastfeeding should be safe, assuming you do not have any other conditions that would make it unsafe.

Is it safe to take melatonin and Nyquil together?

As there is no research that specifically examines the interactions between melatonin and Nyquil, it is impossible to know whether they can be taken together safely. Melatonin is metabolized in the liver, so taking it with medications that are also metabolized in the liver could increase the risk of adverse effects.

Nyquil is a combination of several active ingredients which are metabolized in the liver. This could cause an increased rate of metabolism of melatonin, which could potentially result in a reduction of melatonin’s desired effects.

Can you take melatonin with Benadryl?


Benadryl is a common over-the-counter allergy medicine used for the treatment of allergies such as runny nose, hives, itching, and swelling. Benadryl works by stopping the release of histamine, a chemical released by the immune system that is responsible for allergies. Melatonin is a hormone that is involved in regulating the sleep-wake cycle and circadian rhythms.

There is no evidence that melatonin and Benadryl interact with each other. However, both drugs are metabolized by the liver, so their combined use could increase the liver’s workload. This may result in reduced effectiveness of both medications.

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Summary

Melatonin is a hormone that is involved in several of our body’s functions, including sleep patterns. It is commonly used for sleep disorders such as sleeplessness, jet lag, shift work sleep disorder, and circadian rhythm disorders.

Taking melatonin supplements with Nyquil could cause an increased risk of drowsiness, dizziness, and headaches. There is also a risk that it could negatively interact with other hormones in the body. Melatonin is metabolized in the liver, so taking it with medications that are also metabolized in the liver could increase the risk of adverse effects. T

here is no research that specifically examines the interactions between melatonin and Nyquil, so it is impossible to know whether they can be taken together safely. Both medicines are metabolized in the liver, so their combined use could increase the liver’s workload and reduce the effectiveness of both medications.


David Warren
Author

David Warren is a pharmaceutical specialist that dispenses prescription medication on a daily basis. He received a Bachelor of Science degree in pharmacy from the University of Tennessee in 1991. With over 50 publications on medication-related and pharmacy topics, David has been able to share his experiences and knowledge with others. David with lots of experience and knowledge in medications that are utilized to treat a wide range of medical conditions. Before David dispenses a medication to a patient, he will go over the side effects, dosage recommendation and contraindications.