Zyrtec and Nyquil are both common over-the-counter drugs that can help you feel better if you’re dealing with a cold or the flu. While these two medications have similar functions, they also have some key differences.

These two medicines can be used together in some situations, but generally speaking, it’s best to avoid combining them unless your doctor advises you to do so. Let’s take a look at how using zyrtec and nyquil together could affect you and when it’s okay to take them together.

Zyrtec vs Nyquil: The Basics

Zyrtec is an antihistamine, which means that it blocks the effects of histamines in the body by inhibiting the action of certain receptors. Histamines can cause inflammation, itching, and swelling in the body, including the nose and throat. Zyrtec’s active ingredient, cetirizine hydrochloride, is an antihistamine that is used to treat symptoms of allergies and the common cold and flu, including stuffy or runny nose, sneezing, itching, coughing, and watery eyes.

Zyrtec is a non-sedating antihistamine, so it shouldn’t cause drowsiness, but it does have some side effects, including headaches, diarrhea, abdominal pain, and vomiting.

When Can You Take Zyrtec and Nyquil Together?

Generally, you shouldn’t take zyrtec and nyquil together, but there are some situations where it’s recommended. If you have the flu, you should take zyrtec to help reduce the severity of your symptoms, but you should take nyquil to help you sleep. Similarly, if you have allergies, you should take zyrtec to relieve your symptoms, but you should take nyquil if you also have difficulty sleeping.

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In all other cases, it’s best to avoid combining these two medicines. If you want to use zyrtec and nyquil together, make sure you’re taking the appropriate dose for each medication. You should also be aware that higher doses of nyquil can cause more significant side effects.

Zyrtec Side Effects

As with any medicine, it’s important to know the potential side effects. The most common side effect of taking zyrtec is a mild headache, especially if you take a higher dose. Other side effects include diarrhea, abdominal pain, vomiting, and dizziness. Zyrtec can also cause drowsiness, so it’s important not to drive or operate machinery while taking this medication.

Zyrtec is generally safe to take while pregnant, but it’s important to talk to your doctor first. It’s also safe to take zyrtec while breastfeeding, but you should limit your dosage as much as possible. You can help reduce the likelihood of experiencing side effects by taking zyrtec with food and by taking it at the lowest dosage necessary to manage your allergy or cold symptoms. Y

ou should also avoid taking zyrtec while you’re also taking any other medications.

Nyquil Side Effects

Nyquil is contraindicated for use in individuals under the age of 12, but otherwise it’s generally safe when used as directed. It can cause drowsiness and impaired motor function in adults, but it doesn’t cause drowsiness in children under 12.

Because nyquil can cause drowsiness, it’s important not to drive or operate machinery while taking this medication. It’s also important not to drink alcohol while taking nyquil, as it could increase the drowsiness caused by the drug.

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Nyquil is generally safe to take while pregnant and breastfeeding, but you should talk to your doctor first.

Other Ways to Help You Feel Better from a Cold or the Flu


In addition to taking zyrtec or nyquil, there are a few other ways you can help yourself feel better during a cold or the flu. You should drink plenty of fluids, get plenty of rest, and stay as clean as possible. You should also avoid contact with others as much as possible to minimize the spread of germs. Y

ou can also try using a saline nasal spray or a vaporizer to help relieve nasal congestion, a hot water bottle or a warm blanket to help relieve muscle aches, and a humidifier to keep your sinuses moist. You can also try making some homemade comfort foods, like chicken noodle soup or hot cocoa, to help you feel better.

Final words

No one likes to deal with a cold or the flu, but there are some things you can do to make yourself feel better. Zyrtec and nyquil can help you get through it quicker and easier, but you should only take them together if your doctor advises you to do so.

In most cases, it’s better to take these medications separately so you can minimize their side effects and maximize their benefits. If you’re dealing with a cold or the flu, zyrtec and nyquil can be helpful medicines, but they won’t do any good if you don’t take them. Make sure you get the right dosage and take them as directed to help yourself feel better faster.


David Warren
Author

David Warren is a pharmaceutical specialist that dispenses prescription medication on a daily basis. He received a Bachelor of Science degree in pharmacy from the University of Tennessee in 1991. With over 50 publications on medication-related and pharmacy topics, David has been able to share his experiences and knowledge with others. David with lots of experience and knowledge in medications that are utilized to treat a wide range of medical conditions. Before David dispenses a medication to a patient, he will go over the side effects, dosage recommendation and contraindications.