It’s flu season, and there is nothing more comforting than being wrapped in blankets while you sip on chicken soup and pandora to help you get over it. If you have the munchies as well as a sore throat, then perhaps the best way to go about this is by smoking some weed with Nyquil. This combination has been used for years because of its ability to relieveflu symptoms and provide an excellent high at the same time.

As we all know, using too much of anything can be bad for your health. Weed combined with NyQuil may give you the benefits of both but in excess can lead to side effects; so in this article we will look at the pros and cons of smoking Nyquil weed, what are the effects of Nyquil and weed together, how much should you take, what vENDORS sell it etc..

What is Nyquil?

Nyquil is a brand name for a number of over-the-counter (OTC) cough and cold medicines. It is a combination of different active ingredients intended to relieve cough, congestion, minor pain, and fever while you sleep. Most OTC cough and cold medicines are dextromethorphan (DM), which is commonly used as a cough suppressant, analgesic (pain reliever), and antihistamine.

Other ingredients include pseudoephedrine, acetaminophen, and guaifenesin. The active ingredients in the specific type of NyQuil that we are talking about are acetaminophen, dextromethorphan, and doxylamine succinate.

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What is Weed?

Weed is a slang term for cannabis, a drug made from the dried leaves and flowers of the hemp plant. It’s usually smoked or eaten for medical or recreational purposes. The chemical in weed that causes a ‘high’ is called tetrahydrocannabinol (THC), which comes from the resin produced by the plant.

THC acts on the brain, impacting the chemical receptors that control pleasure, concentration, and sensory perception. Other ingredients found in weed are terpenoids, flavonoids and cannabinoids.

Effects of Smoking Nyquil and Weed Together

Like all drugs, there are potential side effects of smoking Nyquil and weed at the same time. Here are a few that you should watch out for:

  • Dizziness and light-headedness
  • Slower reaction time
  • Lack of coordination and poor balance
  • Drowsiness
  • Dried out mouth
  • Slowed heart rate
  • Lack of blood flow to the heart
  • Breathing problems
  • Hallucinations-
  • Tremors
  • Uncontrolled movements with seizures being a rare symptom
  • Unconsciousness
  • Death


These reactions will be more intense if you combine weed with other medications or alcohol. It’s not recommended to mix weed with alcohol since both depress the central nervous system and can lead to an overdose.

Mixing weed with prescription medications can cause serious side effects.

Pros of Smoking Nyquil and Weed Together

You Feel Better:

This is probably the most obvious benefit of smoking Nyquil and weed together. If you’re not feeling well and you want to get a little bit of relief, this is the perfect combination. Both of these drugs are used to relieve symptoms of the common cold and flu, so this is a great way to get rid of some of those symptoms

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You Sleep Better:

Those of you who are familiar with the effects of weed know that it is a very sedative drug. This means that it promotes sleep, making it a great choice for those who have trouble sleeping.

Great For Daytime:

Although weed is often associated with a “high”, most users are looking to relax and de-stress, not get super stoned. Smoking Nyquil and weed together can alleviate symptoms of anxiety, make you less stressed, and give you a relaxed feeling.

Great For Parties:

For those who like to use weed for social occasions, this is a great combination. You can relax, be in a better mood, and have a good time.

Great For Staying Awake:

For those who work night shifts or have lots of things to do during the day, this combination is perfect. You can stay alert and focused while still having a relaxed feeling.

Cons of Smoking Nyquil and Weed Together

You Can Get Addicted:

Drugs like weed, although they have medicinal purposes, can be addictive. If you’re using this combination regularly, you’re at a higher risk of becoming addicted to weed.

You Can Have a Negative Reaction:

Some people have negative reactions to certain drugs, even when they’re taken for medicinal purposes. This can be especially true when you combine two drugs together.

You Can Overdose:

As we mentioned earlier, both drugs can lead to an overdose if taken too much.

The risk of an overdose is greater when you combine two drugs because you don’t know the amount of each drug your body is receiving.

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You Can Experience Withdrawal Symptoms:

Some people who take weed regularly experience withdrawal symptoms when they try to stop. This can include anxiety, cravings, and other symptoms. Combining weed with other drugs like Nyquil can make withdrawal more likely.

You Can Experience Negative Side Effects:

Although many of the drugs in Nyquil are used to treat the flu and cold, they also have side effects.

For example, acetaminophen can cause liver damage if taken in high doses. The combination of both drugs can lead to even more side effects.


Like with any drug or medication, it’s important to consider the potential side effects and risks before you decide to use it. Cannabis is no exception, and it’s especially important to be aware of the side effects when combining it with other drugs.

Given everything we’ve discussed, it’s clear that smoking Nyquil and weed together can have some serious side effects and risks. That said, it can also provide some benefits like relief from symptoms, relaxation, and social interaction. When used in moderation, these drugs can be helpful and enjoyable.

So if you’re not feeling well and want a quick fix, smoking Nyquil and weed together might be a good option.


David with lots of experience and knowledge in medications that are utilized to treat a wide range of medical conditions. Before David dispenses a medication to a patient, he will go over the side effects, dosage recommendation and contraindications.


  1. Avatar

    Obviously use caution if you’re going to take weed and then Nyquil in the same night, let alone taking either, but more than likely you’ll be alright. You’ll just sleep super well. I’ve done it before, slept throughout the night with no issues, and I woke up fine and energetic as if I took nothing. But don’t worry it’s not a habit. It was only when either feeling under the weather or unable to sleep and nothing else was working. I take it and wake up alert and good as new. And I only take the recommended dose. And I don’t use that much weed as it is. Just one hit or so once in awhile, not everyday. Also, despite that, I’m very healthy. Regular doctor check ups check out fine. I exercise regularly and watch what I eat. So all of that plays a factor into how you’ll react when mixing the two. I’m not condoning it or advocating it. I’m simply saying that I’ve done it numerous times in the past and I’ve always been fine. No issues at all ever. But you know your body chemistry and system best. Just because I’m fine each time doesn’t mean someone else will be. As always bring it up with your doctor on your next visit.

  2. Avatar

    I think that is absolutely necessary to consult a doctor to find out if you can mix any two drugs. I don’t necessarily know how the two will react or what ill-effects they may have. What an arrogrant reply from what is clearly a shady website.

  3. Avatar
    Everett Y.

    This article is pretty redundant. “Mental fog and Drowsiness”? Of course, it’s pot and NyQuil. If you’re gonna use both, you kinda expect that…

  4. Avatar

    Indeed, this text was written by a student in medicine (PhD), we agree it’s best to consult a doctor for (serious) problems/advices, but I think it’s not necessary to consult a doctor to find out if you can mix thc and nyquil…

  5. Avatar

    It’s incredible how poorly articulated (mis)information presented alongside stock photos of doctors can be allowed to pass as authoritative medical advice. Talk to a real doctor if you have concerns.

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