Zofran is an antiemetic (antinausea drug) that is used to treat nausea and vomiting associated with cancer chemotherapy, radiation therapy, and surgery. It is also used to prevent post-operative vomiting in adults. Zofran should not be taken by anyone who has had a recent allergic reaction to ondansetron or related drugs such as dolasetron or palonosetron.

Zofran is a prescription medicine, so it should not be shared with others; it may have serious side effects if you take another person’s dose of zofran.

If you have any questions about zofran, speak to your physician or pharmacist for more information.

What are the ingredients in zofran?

Each tablet of zofran contains: ondansetron hydrochloride (as a white to off-white powder) 0.25 mg, 0.50 mg or 1.00 mg.

What is zofran?

Zofran is an add-on medicine for people with nausea and vomiting caused by chemotherapy, radiation therapy and surgery (chemotherapy-induced nausea and vomiting, radiation-induced nausea and vomiting, and postoperative nausea and vomiting). Zofran is also used for the prevention of nausea and vomiting after surgery in adults who do not have cancer. Zofran can be used alone or with other medicines to treat or prevent nausea and vomiting in people receiving cancer treatment. Zofran belongs to a class of drugs called serotonin 5HT3 receptor antagonists.