Ciclopirox olamide is an active ingredient used in topical products to treat fungal infections. It has a broad spectrum of activity against dermatophytes (fungi that cause skin infections) and other fungi, including
Malassezia species. It also has good affinity for keratin, the main structural protein in hair, nails, and stratum corneum; that makes it effective for reducing sebum production and treating dandruff.
Ciclopirox olamide comes as a solution or foam for application on the affected areas. The usual recommended dosage is twice daily for six weeks. If you want to buy ciclopirox olamide over the counter, keep reading to find out where you can purchase this product without a prescription from your doctor.
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What is Ciclopirox Olamide?
Ciclopirox olamide is a synthetic compound that contains one 4-aminoquinoline ring. It is a broad-spectrum antifungal agent with a keratolytic action used topically to treat skin infections caused by dermatophytes and other fungi.
The term “”ciclopirox”” refers to the cyclopropylmethyl ring in the chemical structure of the molecule. This ring is characteristic for the ciclopirox olamide molecule and distinguishes it from other 4-aminoquinolines.
Ciclopirox olamide has a broad spectrum of activity against dermatophytes (fungi that cause skin infections) and other fungi. It also has good affinity for keratin, the main structural protein in hair, nails, and stratum corneum; that makes it effective for reducing sebum production and treating dandruff.
How Does Ciclopirox Olamide Work?
The ciclopirox olamide molecule is a cyclic tetrahydroquinoline 4-aminoquinoline derivative used topically as a broad-spectrum antifungal agent. The ciclopirox olamide molecule binds to sterols, primarily ergosterol, the essential fungal cell membrane constituent.
This binding results in increased cell membrane permeability and subsequent cell death. In vitro studies indicate that ciclopirox olamide is fungistatic against dermatophytes, yeast, and some molds.
The drug is also bacteriostatic against certain Gram-positive bacteria. Ciclopirox olamide has good affinity for keratin, the main structural protein in hair, nails, and the stratum corneum.
This property makes it effective for reducing sebum production and treating dandruff. Ciclopirox olamide has also demonstrated antiinflammatory activity in vitro against certain polymorphonuclear leukocytes (PMNs).
Side Effects of Ciclopirox Olamide
Ciclopirox olamide is generally well tolerated, but can cause a variety of side effects including itching, burning, pain, irritation, and rash. In rare cases, oral use of ciclopirox olamide can cause nausea, vomiting, abdominal pain, diarrhea, bleeding, dizziness, and drowsiness.
Topical use of ciclopirox olamide can cause allergic contact dermatitis. Ciclopirox olamide should not be used in individuals with implanted medical devices, such as a central venous catheter, or a digital rectal exam due to potential interaction with the device.
Where to Buy Ciclopirox Olamide?
Ciclopirox olamide is available both over the counter and with a prescription. You can buy ciclopirox olamide online or in drugstores that carry the topical treatment for fungal infections of the skin.
If you want to purchase ciclopirox olamide over the counter, you will need to consult a pharmacist to find out the dosage, how often you should apply the medication, and how long the treatment will last.
Reactions to topical treatments vary greatly from one individual to another because of differences in skin type, environment, and bacterial flora. Your pharmacist will be able to help you find the product that best suits your needs.
Is There a Generic Version of Ciclopirox Olamide?
Ciclopirox olamide is a generic drug. It is available under various brand names, including Loceryl, Xolegel, and Cepobrox.
The active ingredient contained in the various formulations of topical ciclopirox olamide is the same, regardless of the manufacturer or brand name.
Conclusion
Ciclopirox olamide is a broad-spectrum antifungal agent used topically to treat fungal infections of the skin. It has good affinity for keratin, the main structural protein in hair, nails, and stratum corneum, making it effective for reducing sebum production and treating dandruff. Ciclopirox olamide is generally well tolerated, but can cause a variety of side effects.
It should not be used in individuals with implanted medical devices, such as a central venous catheter, or a digital rectal exam due to potential interaction with the device. Ciclopirox olamide is available both over the counter and with a prescription, and is also available under various brand names.
