How to Take Liquid Low Dose Naltrexone3 min read

Understanding Liquid Low Dose Naltrexone

Liquid low dose naltrexone (LDN) is a medication that has gained attention for its potential therapeutic benefits in various conditions. LDN is derived from naltrexone, an opioid antagonist primarily used to treat opioid addiction. However, in low doses, LDN is believed to modulate the immune system and have anti-inflammatory effects, offering potential benefits for a range of conditions such as autoimmune diseases, chronic pain, and even certain types of cancer.

Consulting with Your Physician

Before considering the use of liquid low dose naltrexone, it is crucial to consult with your physician or healthcare provider. They will evaluate your medical history, current medications, and specific condition to determine if LDN is a suitable option for you. Additionally, your healthcare provider will guide you on the appropriate dosage and monitor your progress throughout the treatment.

Preparing the Liquid Low Dose Naltrexone

Liquid low dose naltrexone is typically available in a concentrated form and needs to be diluted before consumption. Follow these steps to prepare your LDN solution:

  1. Start with a clean, sterile glass container with a secure lid.
  2. Add the required amount of distilled water or another diluent as directed by your healthcare provider. It is crucial to measure accurately to ensure the correct dosage.
  3. Empty the contents of the LDN bottle into the glass container.
  4. Secure the lid tightly and shake the container vigorously for a few minutes to ensure proper mixing.

Administering Liquid Low Dose Naltrexone

Liquid low dose naltrexone is usually taken orally once daily. Follow these guidelines for administration:

  1. Using an oral syringe or dropper, measure the prescribed dosage accurately. It is important to adhere to your healthcare provider’s instructions regarding the dosage.
  2. Place the measured LDN solution under your tongue and hold it there for one to two minutes. This sublingual route allows for better absorption.
  3. After holding the solution under your tongue, swallow it. You can chase it with water or another beverage if desired.

Important Considerations

While taking liquid low dose naltrexone, it is essential to keep the following points in mind:

  • Consistency: Try to take LDN at the same time each day to maintain a consistent dosing schedule.
  • Avoid Food Interactions: To maximize absorption, it is recommended to take LDN on an empty stomach, at least one hour before or two hours after a meal.
  • Medication Interactions: Inform your healthcare provider about all the medications, supplements, or herbal products you are taking, as they may interact with LDN.
  • Potential Side Effects: Like any medication, liquid low dose naltrexone may have side effects. Common side effects include vivid dreams, sleep disturbances, and temporary changes in liver function. However, these side effects are generally mild and well-tolerated.


Liquid low dose naltrexone is an intriguing medication with potential therapeutic benefits for various conditions. By following the instructions provided by your healthcare provider, preparing the LDN solution correctly, and administering it as directed, you can optimize the potential benefits of this treatment option. Remember to consult with your physician to determine if liquid low dose naltrexone is suitable for your specific situation.